Showing posts with label treatment. Show all posts
Showing posts with label treatment. Show all posts

Tuesday, May 7, 2024

The Retired Consultant Redux – A Conversation With Two Internists

University Hospital of Zürich (Universitätsspital Zürich, USZ) (Ank Kumar, Infosys Limited) 03

In retirement I run into colleagues who are interested in the process and how it is going. I was greeted with a “How is my favorite retired psychiatrist” yesterday. It originated from a highly qualified subspecialist who was immersed in hospital work when I first met him. We talked briefly about his changing roles over the years going from hospital based acute care practice, to an outpatient specialty practice, to his current role of tertiary consultant seeing the most difficult problems in his field. I told him that was the role I miss the most – seeing the most difficult to diagnose and treat cases and being the one to figure out what to do.

It is not an easy life – especially if you are as neurotic as me.  It involves constant research and revision of approaches. It involves close follow up.  It involves sleepless nights and anxiety.  It involves balancing innovation against not wanting to make a mistake.  Sometimes it involves convincing other people to go along with you when they may be reluctant. It also involves tolerating the suffocating routine of excessive documentation and jumping through unnecessary administrative hoops as well as the occasional overt harassment. But in the end – you end up being a physician that both your patients and colleagues can count on and that’s something.

We discussed the nature of treating these populations. He told me he likened his practice to neurology because of the reputation that the level of esoteric diagnoses are not matched by esoteric treatments and often there is not much that you can do. I never understood this degree of pessimism.  I have been confronted with people who told me their last doctor told them: “Look there is nothing more I can do for you.”  And we were able to make some progress.     

Finally – we discussed the 2 year milestone and how many people leave retirement and have to go back into active practice at that point.  He made the observation that this seems to happen across professions where possible – and it seemed to depend on attitudes to retirement and whether you had anything to do.  He did not think retirement would be a problem.  I estimated he had about another 8-10 years of practice left.  I had my usual thoughts about all of the people I knew who never made it to retirement.  I also thought about retirement from physically taxing work and the problems that involves - not the least of which is adjusting caloric intake to prevent excessive weight gain.  

The second conversation was more technical. It was an opinion about gabapentin.  The patient in question was taking it long term for back pain and had a history of back surgeries. More recently she was on diuretics and other medications for atrial fibrillation and congestive heart failure. She was seeing several specialists and they were dutifully getting all of the correct labs but nobody seemed to notice the gradual increase in creatinine to 1.7 and 2.4.  That correlated clinically with increasing somnolence, ataxia, and falls.  After reading the package insert on gabapentin he called me to discuss a dosage adjustment with renal insufficiency.

I recalled a healthy young man I was treating who became acutely confused and ataxic after he was started on simvastatin by a consultant. In psychiatry, this scenario raises suspicions of intoxicants even in a hospital setting. But given the circumstances I decided to also look for a cause of delirium.  The acute labs showed that he had acute renal failure as an idiosyncratic reaction to the statin and he was transferred to medicine to treat the problem.  The acute renal failure led to the accumulation of gabapentin and the delirium and ataxia.

As we discussed the cases, the internist pointed out the difficulty with today’s fragmented medical care.  All of the medication were ordered and the labs were done – but nobody seemed to be paying any attention to how the patient was doing. It reminded him of a quote from one of his mentors George Magnin, MD who used to say to his Medicine residents: “What are you going to do until the doctor gets here?”

That quote struck me as genius both as a motivating factor and the immediate reality of the situation. When you are confronted with a patient who is having a problem – you need to be able to do something about it. That doesn’t mean that you will always know what to do – and if you don’t you at least need to know how to triage the problem so that the patient gets the correct care.  We try to increase the likelihood that will happen by specialization, subspecialization, and settings to match the illnesses with the specialists, but those matches are far from perfect.

I had this experience to illustrate.  I got a call from an emergency medicine physician who was seeing a patient I was treating for bipolar disorder. I knew him and his family very well from years of treatment. The ED doc wanted me to hospitalize him for acute mania but his wife who was with him said he was not manic and she did not want him admitted to a psychiatric unit.  After a brief description of his symptoms I said: “Put him on the phone so I can talk with him.”  Within 30 seconds I could tell he had a fluent aphasia with paraphasic speech errors.  When the ED doc came back on I told him that this was not mania – but most likely an acute stroke syndrome and he was hospitalized on Neurology where the stroke diagnosis was confirmed.

“What are you going to do until the doctor gets here?” – means that doctor.  The one who can diagnose and treat your problem.  That is the one that matters.  In this era of health apps, checklists, self-diagnosis, electronic health records, telemedicine, and so-called artificial intelligence that is still all that matters.

Being that person is hard to attain and hard to walk away from.

 

George Dawson, MD, DFAPA 



Image credit:  Wikimedia Commons per their CC licensing the details of which are available by clicking on the graphic.

Additional:  The identities of the physicians were anonymized in this post. I doubt that any physician benefits from being associated with me or this blog.


Wednesday, February 28, 2024

A Trip To The Dermatologist

 


 

Pattern matching is an important skill for all physicians.  It is rarely discussed these days despite all the continuous hype about artificial intelligence replacing doctors by reading x-rays and other lab tests.  I taught a course in diagnostic reasoning for about 12 years and the examples of pattern matching I used were from dermatology and ophthalmology.   The dermatology experiment was a straightforward comparison of dermatologists to primary care physicians looking at the same slide set of rashes and skin lesions (1).  The dermatologists were correct more often, faster at diagnosing, and able to correctly diagnosis equivocal cases compared with the primary care physicians.

I want to be clear that does not mean that primary care doctors don’t do a good job.  Some are so good that dermatologists know that they need to attend to the diagnosis and treatment of some physicians who refer them significant numbers of patients with melanoma and other types of cancer.  All these factors were probably in my subconscious when I decide to call to see a dermatologist.

It was not easy.  The first appointment was a teleconference and I would call it a swing and a miss. I was given a very expensive prescription for ocular rosacea that did nothing. When I called again to be seen in person, I was given an elaborate algorithm based on how many problems I wanted to be seen about. The more problems – the longer the wait.  I decided to go outside of my usual healthcare providers to a private clinic closer to my home. 

I have noticed a gradual accumulation of dermatology problems with age. I have made every effort to avoid direct sunlight.  If I must be outside at any time when my shadow is shorter than my height, I am wearing a high SPF shirt and sunscreen, a baseball cap, and wrap around polarized sunglasses. I have probably been sunburned twice in my life and tanned once. About 2 years ago I noticed a ring-shaped red lesion on my right forearm.  Every now and then it seemed to burn but generally it was static.  I saw my primary care MD and he did a scraping and potassium hydroxide preparation to see if it was ringworm (tinea corporis). It was not, so he told me to apply the betamethasone ointment that I typically use for eczema to the area.  I did for a couple of weeks and there was no effect.

At about the same time, I happened to notice a blue spot on the lateral aspect of my left ankle.  That is a difficult area to see.  I went into see a primary care MD who used an ophthalmoscope for magnification and concluded it was a collection of pigmented cells that did not look like a melanoma.  She said she would describe it in my chart including recording the diameter so it could be followed along by primary care. 

I described all these problems to the Dermatologist's assistant before he walked in the room.  I had photos of all the dermatology products I had been using and what had been tried in the past.  Even though the pattern matching diagnosis in Dermatology is good, like other areas of medicine – the treatments seem to be hit or miss and even then the response seems to vary over time.  I made a note to myself that I should look for papers claiming that these are placebo treatments or it is just all regression to the mean.  But I doubt that there are any anti-Dermatologists out there complaining about that and too many diagnoses and too many medications.

The intake form that I completed was just 2 pages long and there was an occupation section probably to consider environmental exposures.  When the Dermatologist came in he was very cordial and talkative.  He established that we both went to the same medical school (27 years apart), lived in the same neighborhood while we attended, and knew some of the same professors.  He took the history and clarified the technical points to his assistant who had now become his scribe.  He used a dermatoscope to inspect the lesions and make rapid diagnoses on the right forearm (actinic keratosis), left ankle (fibroma secondary to trauma) and left malar area (actinic keratosis).  He recommended freezing the malar area and forearm with liquid nitrogen and said the fibroma was just a skin reaction to some trauma that did not require treatment. At that point we went into a more detailed discussion of the rosacea and ocular rosacea and failed treatments with doxycycline and tacrolimus.  He recommended a compounded product of azelaic acid, metronidazole, and ivermectin, advised me of the cost, and has his assistant set that up. It was a very efficient process – the diagnoses, freezing treatments, and discussion took about 20 minutes.  At the end all of the follow up, prescriptions, and documentation was done and he was moving on to the next person.

There are times when it pays to see an expert and this is an illustration of one of those times.  I had been looking at these lesions for 2 years and trying to take the next steps.  There are as many barriers to seeing a Dermatologist as there are to seeing a psychiatrist.  I knew enough to monitor these lesions and they did not seem to get worse, but they were also not improving. After 2 years I got the definitive diagnoses and treatment I had been looking for as well as reassurance that the ankle lesion was not a melanoma.

This is an impressive result compared with most physician visits.  Even considering that there were a couple of things that did not fit.  Sun exposure for one.  I am what is referred to as a white fish in upper Midwest vernacular.  That means apart from my blue veins and the redness of rosacea – my skin is generally as white as the background of this page.  I had some early exposure to people with skin cancer and have been very diligent about keeping my skin and retinal exposure to direct sunlight at a minimum.  I suppose there are other factors at play such as age and know there are senile keratoses – but this did not resemble typical lesions in my dermatology texts or online. The Dermatologist predicted that the freezing treatment would cause these lesions to slough off and be replaced by normal smooth skin.  I have a follow up in 3 months to see if that happens and if the compounded topical rosacea medication works.

I am currently studying high prevalence polygenic diseases and have included eczema on that list.  Some estimates say that 20% of the population may have it.  There is the association with asthma but in my case as my asthma improved with age, I developed eczema and then worsening eczema.   I expect there will be many parallels with psychiatric disorders and diseases when my comparison is done. 

In the meantime, a Dermatologist in the right setting is a good consultant to have in your corner.

 

George Dawson, MD, DFAPA

 

References:

1:  Norman, G.R., Brooks, L.R., Rosenthal, D., Allen, S.W., & Muzzin, L.J. (1989). The development of expertise in dermatology. Archives of Dermatology, 125, 1063–1068

 This is the original reference I used in my course on the diagnostic process and how not to make a mistakes.  The first author has written significant papers about this.  

Graphic:

I mapped the dermatology conditions onto the body outline. If someone has a better body outline or one that they use on a standardized form and you want to send it my way - please do.  I can make a much better graphic if the outline is a separate shape.  The actinic keratoses areas on the map are probably both only 2 cm in diameter.  The rosacea can happen anywhere on the face and most annoyingly on the eyelids.  The eczema is a whole body condition that started out subtly as intense pruritis on the extremities and eventually spread to the abdominal area, chest, and back.  Pruritis is the most significant symptom with occasional lesions that looks like abrasions.  It can be exacerbated by skin contact with allergens like ECG electrodes.