Showing posts with label China. Show all posts
Showing posts with label China. Show all posts

Friday, January 16, 2026

How To Address the Opioid Crisis Without Gunboat Diplomacy


 

The United States is currently suffering through the self-inflicted crisis of electing an authoritarian administration.  Civil, legal, international, and diplomatic standards are routinely ignored and there seems to be no clear overriding strategy other than promulgating the autocracy.   271,000 government employees were fired, many leading experts in fields that ran counter to the autocratic myths, but most were loyal career government employees dedicated to serve the public.  USAID – a government agency providing technical assistance and medical care in the developing world since 1961 was officially shut down by the Trump administration in 2025.  USAID was credited with saving 92 million lives over 20 years and there is currently a tracker in place that estimates how many people will die as a result of the closure.  It is clear the Trump administration is not afraid to be directly responsible for the deaths of tens of thousands if not millions of people.  It might fit their American first narrative if there was any possible benefit to Americans.  Their political calculus apparently ignores any goodwill effects of helping people and a national image unlike the usual totalitarian regimes.

Trump’s version of the War on Drugs, is smaller in scale but probably much more deadly.  Trump began sinking boats in the Caribbean and the Pacific Ocean that he alleged were carrying drugs in September 2025.  Since then, 35 vessels were struck or sunk killing 123 people (1).  There is ongoing debate that this is not standard drug interdiction where drug smugglers are stopped by the Coast Guard, arrested, and stand trial.  This is unlawful killing of suspected drug smugglers where the public is supposed to accept that the alleged intelligence about whether they were smuggling drugs is accurate.  Given this administration’s honesty track record there is no way that should be accepted at face value.  The Coast Guard’s own statistics suggests that 25% of the vessels they board for the same reason are not carrying drugs. Even if they were this is essentially executing people without due process for what are non-capital crimes in the US.

In addition to the strikes that are seen as criminal there have been 2 incidents suggesting additional war crimes.  In the first, survivors of the first strike were killed while they were swimming in the water.  In the second, a strike was made by a plane disguised as a civilian plane.  According to the Geneva Convention it is a war crime to feign protected status and then attempt to kill, capture, or injure an adversary.  This is known as perfidy and it is accepted by the US.  Like most activity from this administration there appears to be no clear rationale for all this activity and despite the outcry over potential war crimes – the actions continue unabated.

I had plenty of experience teaching diverse groups of students about the opioid epidemic from about 2008 to 2020.   Overdose deaths were a proxy for the epidemic.  The initial part of that curve was due to excessive prescribing that was associated with a pain as the fifth vital sign initiative.  There were excessive and escalating prescriptions for the treatment of chronic pain.  In many cases there were diversions of these drug supplies for non-prescription use.  In some cases, there were pill mills that specialized in writing opioid prescriptions in great numbers.  They resembled medical practices from the turn of the 20th century that maintained people in addiction rather than treating any specific medical problems. As more prescription opioids were diverted it was more cost effective to purchase heroin and that was the first significant change in consumed opioid composition.  By 2014 synthetic opioids (fentanyl and carfentanyl)  were introduced into this landscape.  They had much higher potency than the usual prescription opioids and that led to more drug overdoses.  Countermeasures were introduced including intranasal naloxone and fentanyl test kits.  These are effective measures if available but there is some misunderstanding by the public, who sees opioid users as risk averse.  They are not risk averse but both countermeasures are useful in saving lives.  The most effective life saving measure is MOUD or medication for opioid use disorder including buprenorphine, methadone, and naltrexone.

That brings me to a paper on the sudden reduction in overdose deaths beginning in mid-2023 and extending into 2025 in both the US and Canada.  During that time the overdose death rates dropped by 30%(3).  The graph of that reduction is shown below.  The data is a combination of confirmed data by the CDC and provisional counts and projections by NCHS for the last two years.  It is very similar to the graphs generated by the authors in their report.

 


 The authors used a novel approach to investigate the idea that supply shock accounts for the decrease in overdose deaths.  During treatment it is common for people using non-prescription controlled substances to report shortages and changes in the drug supply as well as price changes to their treatment providers.  The authors used the number of drug seizures and opioid concentration estimates of those seizures to estimate fentanyl shortages.  They also searched a popular social media site (Reddit) for any mention of the term fentanyl or a reasonable facsimile and drought or shortage or a facsimile.  The Reddit data was compromised from January to July of 2024 by moderation on the basis that these posts about fentanyl shortages violated terms of use.

Both groups of indicators of decreased drug supply (drug seizures and concentration and social media posts indicating a drug shortage) correlated with a drop in drug overdose deaths.  By the end of 2024 the opioid overdose death rates and concentrations has fallen by about 30% (see graph).  The original paper plots both fentanyl concentration in pills and powders as well as death rates).

What caused these drops?  The authors suggest several possibilities.  First, China acted against the manufacture and sale of fentanyl and the precursors starting in late 2023. That included online platforms.  There was a meeting between President Biden and Xi in November 2023 that focused on law enforcement cooperation in this area.  The authors suggest this is a low-cost opportunity for China to get leverage in negotiations with the US. Second, US drug interventions in Mexico may have reduced the supply, but the authors point out that the DEA would have paradoxically claimed no credit in their reporting but did credit the lack of precursors from China.  These factors are strong arguments for supply chain disruption as a cause of the drop in opioid overdose deaths.  

Could this be a generational effect?  From a demographic standpoint, the 25-plus year opioid epidemic represents an entire generation.  The succeeding generation has seen the toll of these drugs as both mortality and morbidity.  The younger generation has been noted to have some sober initiatives and they are consuming less alcohol that their predecessors. Is it possible that this subcultural movement is extended to other intoxicants?  The 0-25 year age group typically has the lowest number of overdose deaths and by itself is unlikely to account for the decrease.

The authors suggest three implications of their paper.  First, that dealer level interdiction on the street may not be necessary to reduce drug trafficking.  Presumably that intervention has been constant over the course of the recorded data and it has had minimal impact. It is also high risk and places certain demographic groups at higher risk.  Second, this may be a transient effect.  Drug traffickers can adapt as noted by the difference in how fentanyl makes it to the streets in the US compared to Canada.  Finally, if this was in fact the effect of diplomacy those efforts should be increased rather than decreased. India is a source of precursors and in some cases direct to consumer shipments of controlled substances.  Diplomatic efforts could yield further disruptions in the supply chain and less problems with opioids on the streets of the US.       

There is now a fourth implication and that is that gunboat diplomacy and the questionable use of the US military against boats suspected of carrying drugs is unnecessary.  It also highlights that the Executive order to declare war on cartels was also unnecessary.  There was a substantial drop in overdose deaths before any of these measures was employed and it may be an indication that diplomacy is the way forward.  If I was a conspiracy theorist, I would suggest that Trump wants to get credit for the drop in fentanyl trafficking that occurred in the Biden administration.  According to the authors of this paper we do not know if this is a long-term trend or not. Since most fentanyl trafficking does not originate in Venezuela or the countries surrounding the targeted areas it is unlikely to have a big effect.  

That 30% decrease in mortality cannot be ignored and a closer examination of the Biden negotiations is warranted.

 


 

 

George Dawson, MD, DFAPA


References:

1:  Watson B, Peniston B.  The D Brief: ‘Perfidy’ in boat strike?; Pentagon’s new AI plan; Venezuela’s broken air defenses; Quantum space cameras; And a bit more.  Defense One.  January 13, 2026.  https://www.defenseone.com/threats/2026/01/the-d-brief-january-13-2026/410643/

2:  Tait R. Killing of survivors sparks outrage – but entire US ‘drug boat’ war is legally shaky.  The Guardian.  December 4, 2025.  https://www.theguardian.com/us-news/2025/dec/04/venezuela-boat-strikes-legality-hegseth

3:  Vangelov K, Humphreys K, Caulkins JP, Pollack H, Pardo B, Reuter P. Did the illicit fentanyl trade experience a supply shock? Science. 2026 Jan 8;391(6781):134-136. doi: 10.1126/science.aea6130. Epub 2026 Jan 8. PMID: 41505547.

Graphics:

1:  Lead graphic is from the CDC and is in the public domain: https://www.cdc.gov/overdose-prevention/about/understanding-the-opioid-overdose-epidemic.html

2:  The graph of fatal overdose deaths per year shows the number of fatal opioid overdose deaths in the United States from 2000 to 2025.  The data from 2000 to 2023 consists of final and reported figures from the Centers for Disease Control and Prevention (CDC) and the National Institute on Drug Abuse (NIDA). The figures for 2024 and 2025 are based on provisional counts and projections released by the CDC's National Center for Health Statistics (NCHS) as of January 2026.

3:  Graphics 2 and 3 were designed with the assistance of Google Gemini.